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Yuji Komizu Selected Research

Dimyristoylphosphatidylcholine (DMPC)

1/2016Targeting ceramide synthase 6-dependent metastasis-prone phenotype in lung cancer cells.
6/2013Hybrid liposomes inhibit tumor growth and lung metastasis of murine osteosarcoma cells.
2/2012Hybrid liposomes inhibit growth and invasion of human osteosarcoma cells leading to apoptosis.
2/2012Selective accumulation and growth inhibition of hybrid liposomes to human hepatocellular carcinoma cells in relation to fluidity of plasma membranes.
7/2011Selective accumulation of hybrid liposomes into adult T-cell leukemia cells along with induction of apoptosis.
1/2011Remarkable inhibitory effects of hybrid liposomes on growth of human colon cancer cells through induction of cell cycle arrest along with apoptosis.
1/2011[Experimental therapeutic effects of hybrid liposomes on the Alzheimer's disease in vitro].
1/2011Therapeutic effects of hybrid liposomes composed of phosphatidylcholine and docosahexaenoic acid on the hepatic metastasis of colon carcinoma along with apoptosis in vivo.
6/2010Hybrid liposomes inhibit the growth of cholangiocarcinoma by induction of cell cycle arrest in G1 phase.
12/2006Membrane targeted chemotherapy with hybrid liposomes for colon tumor cells leading to apoptosis.

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Yuji Komizu Research Topics

Disease

11Neoplasms (Cancer)
01/2016 - 12/2006
5Neoplasm Metastasis (Metastasis)
11/2019 - 01/2011
3Lung Neoplasms (Lung Cancer)
11/2019 - 01/2016
3Infections
02/2015 - 03/2010
2Osteosarcoma (Osteogenic Sarcoma)
06/2013 - 02/2012
2Hepatocellular Carcinoma (Hepatoma)
07/2012 - 02/2012
2Carcinoma (Carcinomatosis)
01/2011 - 10/2008
2Primary Effusion Lymphoma
07/2010 - 03/2010
1Carcinogenesis
08/2021
1Liver Neoplasms (Liver Cancer)
01/2019
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2016
1Wounds and Injuries (Trauma)
02/2012
1Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated)
07/2011
1Colonic Neoplasms (Colon Cancer)
01/2011
1Alzheimer Disease (Alzheimer's Disease)
01/2011
1Neuroblastoma
01/2011
1Cholangiocarcinoma
06/2010

Drug/Important Bio-Agent (IBA)

18Liposomes (Liposome)IBA
01/2019 - 12/2006
10Dimyristoylphosphatidylcholine (DMPC)IBA
01/2016 - 12/2006
8Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
06/2013 - 12/2006
5Ether (Diethyl Ether)IBA
06/2013 - 12/2006
3dihydroceramide desaturaseIBA
11/2019 - 01/2016
3Therapeutic UsesIBA
06/2013 - 01/2011
3LipidsIBA
02/2012 - 01/2011
3EthersIBA
02/2012 - 01/2011
2Caspase 3 (Caspase-3)IBA
02/2012 - 07/2011
1Epithelial Cell Adhesion MoleculeIBA
01/2019
1Proteins (Proteins, Gene)FDA Link
01/2019
1RV 538 (PDMP)IBA
01/2016
1CeramidesIBA
01/2016
1SphingolipidsIBA
01/2016
1ceramide glucosyltransferaseIBA
01/2016
1GUT-70IBA
02/2015
1cepharanthineIBA
05/2014
1CaspasesIBA
07/2012
1matrigelIBA
02/2012
1Docosahexaenoic AcidsIBA
01/2011
1Unithiol (DMPS)IBA
01/2011
1Amyloid (Amyloid Fibrils)IBA
01/2011
1Ammonium CompoundsIBA
01/2011
1Phospholipids (Phosphatides)FDA LinkGeneric
01/2011
1Peptides (Polypeptides)IBA
01/2011
1PropaneIBA
01/2011
1Phosphatidylcholines (Phosphatidylcholine)IBA
01/2011
1dimyristoylphosphatidylserineIBA
01/2011

Therapy/Procedure

6Drug Therapy (Chemotherapy)
06/2013 - 12/2006
1Cell Transplantation
08/2021
1Therapeutics
01/2019
1Intravenous Injections
01/2011